3-d]pyriMidine-6-carboxylate

3-d]pyriMidine-6-carboxylate - Names and Identifiers

Name	1H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-, ethyl ester
Synonyms	3-d]pyriMidine-6-carboxylate Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyriMidin-6-carboxylate Ethyl 4-chloro-1H-pyrrolo[2,3-d]pyrimidine-6-carboxylate ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate 4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-6-carboxylic acid ethyl ester 4-Chloro-7H-pyrrolo[2,3-d]pyriMidine-6-carboxylic acid ethyl ester 1H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-, ethyl ester ETHYL 4-CHLORO-7HPYRROLO[2,3-D]PYRIMIDINE-6-CARBOXYLATE 1H-PYRROLO[2,3-D] PYRIMIDINE-6-CARBOXYLIC ACID
CAS	187725-00-4
InChI	InChI=1/C9H8ClN3O2/c1-2-15-9(14)6-3-5-7(10)11-4-12-8(5)13-6/h3-4H,2H2,1H3,(H,11,12,13)

3-d]pyriMidine-6-carboxylate - Physico-chemical Properties

Molecular Formula	C9H8ClN3O2
Molar Mass	225.63
Density	1.53±0.1 g/cm3(Predicted)
Boling Point	356.1±52.0 °C(Predicted)
pKa	9.47±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.644

3-d]pyriMidine-6-carboxylate - Risk and Safety

Hazard Class

IRRITANT

3-d]pyriMidine-6-carboxylate - Introduction

1h-yrrolo [2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-, ethyl ester chemical formula C9H7ClN4O2, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 1H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-chlorophyll-, ethyl ester is a white solid.
-Solubility: It can be dissolved in organic solvents, such as ethanol, chloroform and dimethyl sulfoxide.
-Melting point: Its melting point is about 214~217 ℃.

Use:
-1h-yrrolo [2,3-d]pyrimidine-6-carboxylic acid, 4-chlorophyll-, ethyl ester is an organic reagent widely used in drug synthesis. It can be used to synthesize drugs and compounds containing a pyrrole [2,3-d] Pyrimidine skeleton.
-It is also commonly used in organic synthesis reactions as a 1,3-carbonyl addition reagent.

Method:
- 1H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-, ethyl ester is generally prepared by converting 4-chloro-7h-pyrrole [2,3-d]pyrimidine-6-carboxylic acid reacts with ethanol to give the corresponding esterified product. Specific reaction conditions can be optimized according to specific experimental requirements.

Safety Information:
-1h-pyramid [2,3-d]pyrimidine-6-carboxylic acid, 4-chlorophyll-, ethyl ester should be stored and used in accordance with chemical safety procedures.
-It is an organic compound and may have irritating effects on the skin, eyes and respiratory system. Direct contact should be avoided.
-In the process of operation, should wear appropriate protective equipment, such as laboratory gloves, goggles, face shield, etc.
-Any specific safety instructions for this compound should be implemented in accordance with specific laboratory regulations and safety requirements.

Last Update：2024-04-09 02:00:43